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NFL ODDS WEEK 6: HOW TO BET JAGUARS-COLTS, PICK

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In a Week 6 encounter, the Jacksonville Jaguars (2-3) travelled to Indianapolis to take on the Colts (2-2-1).

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The point spread, NFL odds, and other pertinent information are provided here for Sunday's game between Jacksonville and Indianapolis.

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total Over/Under, moneyline, and expert selection (with all NFL odds via FOX Bet).

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Jags against. Colts (1 p.m. ET Sunday, CBS) Colts 2.5 on the point spread (Colts favoured to win by more than 2.5 points, otherwise Jaguars cover)

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Jaguars +110 underdogs to win (bet $10 to win $21 total); Colts -138 favourites to win (bet $10 to win $17.26 total).

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In his career, as a starter while a road underdog, Trevor Lawrence is 3-7 against the spread (ATS) and 1-9 straight up (SU).

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Bears fall to Commanders in low-scoring affair | Game Recap