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Watch the SpaceX rocket carrying the Crew-5 mission take off.

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Today, the historic Crew-5 mission is poised to launch from Florida's NASA Kennedy Space Center.

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Four astronauts are scheduled to embark on SpaceX's Dragon Endurance spaceship, including two who will make history by becoming the first humans to travel to space.

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NASA astronauts Josh Cassada and Nicole Mann are part of the crew.

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Mann will go down in history as the first native American NASA astronaut. She will also be the first female crew capsule commander on the Dragon.

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The first Russian cosmonaut on the SpaceX Crew Dragon will be Anna Kikina of Roscosmos.

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Koichi Wakata, an astronaut with the Japan Aerospace Exploration Agency (JAXA), will also fly with the mission.

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Because to Hurricane Ian's catastrophic route through Florida last week, the launch was postponed by a few days. Now, the launch is anticipated to occur today at 12 PM ET.